منابع مشابه
Pharmacological actions of cannabinoids.
Mammalian tissues express at least two types of cannabinoid receptor, CB1 and CB2, both G protein coupled. CB1 receptors are expressed predominantly at nerve terminals where they mediate inhibition of transmitter release. CB2 receptors are found mainly on immune cells, one of their roles being to modulate cytokine release. Endogenous ligands for these receptors (endocannabinoids) also exist. Th...
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The contribution which alcohol may make to a man's nutrition varies considerably. Alcohol is not an essential dietary constituent, but it is commonly consumed, and unlike most foods it has notable subjective and objective effects in quantities which contribute trivially to the total daily calories. Moderate drinkers are much commoner than those who consume to excess, and it will therefore be mo...
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We assume that phenylephrine produces late pharmacological preconditioning through the opening of the mitochondrial KATP channels. To test this hypothesis, rat hearts were isolated and perfused with Krebs buffer solution by Langendorff method and subjected to 30 min regional ischemia followed by 60 min of reperfusion. In this study, phenylephrine as a selective alpha1-adrenoceptor agonist and 5...
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CARDIPRO is a polyhedral anti-oxidant and cardiotonic formulation recommended to be used in various cardiovascular disturbances, effect of CARDIPRO on different in vitro and in vivo cardiovascular responses were studied. CARDIPRO produced hypotensive effect in dogs and rabbits. The effect was blocked by prior atropinization, CARDIPRO also potentiated and prolonged the beta receptor mediated hyp...
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Sir Ram Nath Chopra (1882-1973) was a pioneer in the field of experimental pharmacology of indigenous drugs of India. Most of the medicinal plants he studied were in use, in ayurveda, for thousands of years. At the Calcutta School of Tropical Medicine, he pioneered a paradigm, a pace and a pattern of research in studying the actions of medicinal plants, which influenced an entire generation of ...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1974
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)32359-5